2018. Francis, E.A., and V. Heinrich. Mechanistic understanding of single-cell behavior is essential for transformative advances in biomedicine. The Yale Journal of Biology and Medicine 91(3):279-289. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153630/
2018. Francis, E.A., and V. Heinrich. Extension of chemotactic pseudopods by nonadherent human neutrophils does not require or cause calcium bursts. Science Signaling 11(521):eaal4289. doi.org/10.1126/scisignal.aal4289 || Full text || Reprint
2017. Heinrich, V., W.D. Simpson III, and E.A. Francis. Analytical prediction of the spatiotemporal distribution of chemoattractants around their source: Theory and application to complement-mediated chemotaxis. Frontiers in Immunology 8(578). doi.org/10.3389/fimmu.2017.00578
2017. Francis, E.A., and V. Heinrich. Quantifying the sensitivity of human immune cells to chemoattractant. Biophysical Journal 112:834-837. doi.org/10.1016/j.bpj.2017.01.009 || PDF 1216 KB
2015. Morikis, V.A., C. Radecke, Y. Jiang, V. Heinrich, F.R. Curry, and S.I. Simon. Atrial natriuretic peptide down-regulates neutrophil recruitment on inflamed endothelium by reducing cell deformability and resistance to detachment force. Biorheology 52(5-6):447-463. doi:10.3233/BIR-15067
2015. Heinrich, V. Controlled one-on-one encounters between immune cells and microbes reveal mechanisms of phagocytosis. Biophysical Journal 109:469-476. doi:10.1016/j.bpj.2015.06.042 || PDF 1177 KB
2015. Lee, C.-Y., G.R. Thompson III, C.J. Hastey, G.C. Hodge, J.M. Lunetta, D. Pappagianis, and V. Heinrich. Coccidioides endospores and spherules draw strong chemotactic, adhesive, and phagocytic responses by individual human neutrophils. PLoS ONE 10(6):e0129522. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0129522
2014. Wangdi, T., C.-Y. Lee, A.M. Spees, C. Yu, D.D. Kingsbury, S.E. Winter, C.J. Hastey, R.P. Wilson, V. Heinrich, and A. Bäumler. The Vi capsular polysaccharide enables Salmonella enterica serovar Typhi to evade microbe-guided neutrophil chemotaxis. PLOS Pathogens 10(8):e1004306. https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1004306 || PDF 3912 KB
2013. Mankovich, A.R., C.-Y. Lee, and V. Heinrich. Differential effects of serum heat treatment on chemotaxis and phagocytosis by human neutrophils. PLoS ONE 8(1): e54735. doi:10.1371/journal.pone.0054735 || PDF 907 KB
2011. Heinrich, V., and C.-Y. Lee. Blurred line between chemotactic chase and phagocytic consumption: An immunophysical, single-cell perspective. Journal of Cell Science 124(18):3041-3051. doi:10.1242/jcs.086413 || PDF 3389 KB
2011. Lee, C.-Y., M. Herant, and V. Heinrich. Target-specific mechanics of phagocytosis: Protrusive neutrophil response to zymosan differs from the uptake of antibody-tagged pathogens. Journal of Cell Science 124(7):1106-1114. doi:10.1242/jcs.02876 || PDF 1104 KB
2011. Herant, M., C.-Y. Lee, M. Dembo, and V. Heinrich. Protrusive push versus enveloping embrace: Computational model of phagocytosis predicts key regulatory role of cytoskeletal membrane anchors. PLoS Computational Biology 7(1): e1001068. doi:10.1371/journal.pcbi.1001068 || PDF 274 KB
2010. Ounkomol, C., S. Yamada, and V. Heinrich. Single-cell adhesion tests against functionalized microspheres arrayed on AFM cantilevers confirm heterophilic E- and N-cadherin binding. Biophysical Journal 99:L100-L102. doi:10.1016/j.bpj.2010.11.013 || PDF 369 KB
2009. Lam, J., M. Herant, M. Dembo, and V. Heinrich. Baseline mechanical characterization of J774 macrophages. Biophysical Journal 96:248-254. doi:10.1529/biophysj.108.139154 || PDF 768 KB
2009. Ounkomol, C., H. Xie, P.A. Dayton, and V. Heinrich. Versatile horizontal force probe for mechanical tests on pipette-held cells, particles, and membrane capsules. Biophysical Journal 96:1218-1231. doi:10.1016/j.bpj.2008.10.047 || PDF 1593 KB
2008. Heinrich, V., and C. Ounkomol. Biophysics in reverse: Using blood cells to accurately calibrate force-microscopy cantilevers. Applied Physics Letters 92(15):153902. doi:10.1063/1.2909529 || PDF 616 KB
2008. Heinrich, V., W.P. Wong, K. Halvorsen, and E. Evans. Imaging biomolecular interactions by fast three-dimensional tracking of laser-confined carrier particles. Langmuir 24:1194-1203. doi:10.1021/la7027059 || PDF 572 KB
2007. Heinrich, V., and C. Ounkomol. Force versus axial deflection of pipette-aspirated closed membranes. Biophysical Journal 93:363-372. doi:10.1529/biophysj.107.104091 || PDF 410 KB
2006. Kim, S.V., W.Z. Mehal, X. Dong, V. Heinrich, M. Pypaert, I. Mellman, M. Dembo, M.S. Mooseker, D. Wu, and R.A. Flavell. Modulation of cell adhesion and motility in the immune system by Myo1f. Science 314:136-139. doi:10.1126/science.1131920 || PDF 404 KB
2006. Vullev, V.I., J. Wan, V. Heinrich, P. Landsman, P.E. Bower, B. Xia, B. Millare, and G. Jones. Nonlithographic Fabrication of Microfluidic Devices. Journal of the American Chemical Society 128:16062-16072. doi:10.1021/ja061776o || PDF 1324 KB
2006. Herant, M., V. Heinrich, and M. Dembo. Mechanics of neutrophil phagocytosis: experiments and quantitative models. Journal of Cell Science 119:1903-1913. doi:10.1242/jcs.02876 || PDF 727 KB
2005. Heinrich, V., and W. Rawicz. Automated, high-resolution micropipet aspiration reveals new insight into the physical properties of fluid membranes. Langmuir 21(5):1962-1971. doi:10.1021/la047801q || PDF 404 KB
2005. Herant, M., V. Heinrich, and M. Dembo. Mechanics of neutrophil phagocytosis: behavior of the cortical tension. Journal of Cell Science 118(9):1789-1797. doi:10.1242/jcs.02275 || PDF 731 KB
2005. Heinrich, V., A. Leung, and E. Evans. Nano-to-microscale mechanical switches and fuses mediate adhesive contacts between leukocytes and the endothelium. Journal of Chemical Information and Modeling 45(6):1482-1490. doi:10.1021/ci0501903 || PDF 415 KB
2005. Evans, E., V. Heinrich, A. Leung, and K. Kinoshita. Nano- to microscale dynamics of P-selectin detachment from leukocyte interfaces. I. Membrane separation from the cytoskeleton. Biophysical Journal 88(3):2288-2298. doi:10.1529/biophysj.104.051698 || PDF 361 KB
2005. Heinrich, V., A. Leung, and E. Evans. Nano- to microscale dynamics of P-selectin detachment from leukocyte interfaces. II. Tether flow terminated by P-selectin dissociation from PSGL-1. Biophysical Journal 88(3):2299-2308. doi:10.1529/biophysj.104.051706 || PDF 319 KB
2005. King, M.R., V. Heinrich, E. Evans, and D.A. Hammer. Nano-to-micro scale dynamics of P-selectin detachment from leukocyte interfaces. III. Numerical simulation of tethering under flow. Biophysical Journal 88(3):1676-1683. doi:10.1529/biophysj.104.051805 || PDF 144 KB
2004. Evans, E., A. Leung, V. Heinrich, and C. Zhu. Mechanical switching and coupling between two dissociation pathways in a P-selectin adhesion bond. Proceedings of the National Academy of Sciences USA 101(31):11281-11286. doi:10.1073/pnas.0401870101 || PDF 452 KB
2004. Wong, W.P., V. Heinrich, and E. Evans. Exploring reaction pathways of single-molecule interactions through the manipulation and tracking of a potential-confined microsphere in three dimensions. In Materials Research Society Symposium Proceedings. Fourkas, J.T., P. Levitz, M. Urbakh, K.J. Wahl, Editors. Materials Research Society, P5.1.1-P5.1.12. PDF 1097 KB
2003. Evans, E., V. Heinrich, F. Ludwig, and W. Rawicz. Dynamic tension spectroscopy and strength of biomembranes. Biophysical Journal 85(4):2342-2350. doi:10.1016/S0006-3495(03)74658-X || PDF 203 KB
2003. Evans, E., and V. Heinrich. Dynamic strength of fluid membranes. Comptes Rendus Physique 4(2):265-274. doi:10.1016/S1631-0705(03)00044-6 || PDF 259 KB
2002. Evans, E., V. Heinrich, and A. Leung. Receptor-cytoskeletal unbinding in detachment of P-selectin from PSGL-1 on leukocytes. In Proceedings of the Second Joint EMBS/BMES Conference. 580-581. doi:10.1109/IEMBS.2002.1136960 || PDF 192 KB
2001. Heinrich, V., K. Ritchie, N. Mohandas, and E. Evans. Elastic thickness compressibility of the red cell membrane. Biophysical Journal 81(3):1452-1463. doi:10.1016/S0006-3495(01)75800-6 || PDF 513 KB
2001. Bozic, B., V. Heinrich, S. Svetina, and B. Zeks. Shapes of nearly cylindrical, axisymmetric bilayer membranes. European Physical Journal E 6(1):91-98. doi:10.1007/s101890170031 || PDF 271 KB
1999. Heinrich, V., B. Bozic, S. Svetina, and B. Zeks. Vesicle deformation by an axial load: from elongated shapes to tethered vesicles. Biophysical Journal 76(4):2056-2071. doi:10.1016/S0006-3495(99)77362-5 || PDF 281 KB
1999. Kralj-Iglic, V., V. Heinrich, S. Svetina, and B. Zeks. Free energy of closed membrane with anisotropic inclusions. European Physical Journal B 10(1):5-8. doi:10.1007/s100510050822 || PDF 272 KB
1997. Heinrich, V., F. Sevsek, S. Svetina, and B. Zeks. Large deviations of the average shapes of vesicles from equilibrium: Effects of thermal fluctuations in the presence of constraints. Physical Review E 55(2):1809-1818. doi:10.1103/PhysRevE.55.1809 || PDF 249 KB
1997. Svetina, S., B. Bozic, V. Heinrich, and B. Zeks. Mechanical properties of membranes and cell polarity. In Proceedings of the Adriatico Research Conference on Nonlinear Cooperative Phenomena in Biological Systems. Matsson, L., Editor. World Scientific Publishing Co. Pte. Ltd., 227-241.
1997. Svetina, S., B. Bozic, V. Heinrich, and B. Zeks. Formation and mechanical properties of membrane nanotubes. Cellular & Molecular Biology Letters 2(suppl. 1):131-149.
1996. Heinrich, V., and R.E. Waugh. A piconewton force transducer and its application to measurement of the bending stiffness of phospholipid membranes. Annals of Biomedical Engineering 24(5):595-605. doi:10.1007/BF02684228 || PDF 1689 KB
1993. Heinrich, V., S. Svetina, and B. Zeks. Nonaxisymmetric vesicle shapes in a generalized bilayer-couple model and the transition between oblate and prolate axisymmetric shapes. Physical Review E 48(4):3112-3123. doi:10.1103/PhysRevE.48.3112 || PDF 2471 KB
1993. Heinrich, V., S. Svetina, and B. Zeks. Shapes of phospholipid vesicles: A generalized bilayer couple model. Acta Pharmaceutica 43:79-82.
1992. Heinrich, V., M. Brumen, R. Heinrich, S. Svetina, and B. Zeks. Nearly spherical vesicle shapes calculated by use of spherical harmonics – Axisymmetric and nonaxisymmetric shapes and their stability. Journal de Physique II 2(5):1081-1108. doi:10.1051/jp2:1992188 || PDF_(poor_quality)_734 KB